Our research programme is dedicated to advancing a comprehensive understanding of malaria epidemiology through an integrated lens of genomics, immunology, transmission biology, and human behaviour. We investigate the genetic mechanisms that drive drug and diagnostic resistance, the emergence of vaccine escape variants, and the shifting landscape of non falciparum malaria species such as P. malariae, P. vivax, and P. ovale. By combining high resolution molecular surveillance with experimental infections, we explore the natural determinants of malaria transmission, including antigenic variation and parasite persistence during the dry season.
In parallel, we examine the social and immunological dimensions of vaccination — from vaccine hesitancy to host immune responses — to better understand how behavioral and biological factors shape public health outcomes. Our research also aims to evaluate the therapeutic efficacy of antimalarial interventions, generating evidence that informs treatment policies and early detection of declining drug efficacy. Together, these efforts form a multidisciplinary platform aimed at strengthening malaria control and elimination strategies, improving diagnostic and therapeutic tools, and anticipating the evolutionary trajectories of malaria parasites in diverse ecological and social contexts.
